However, in Safe Mode there is no straight way to uninstall most programs as in the normal mode. Because when the computer is in safe mode, the required Windows Installer service isn’t started so most programs can’t be uninstalled.
If you trying to uninstall a program in Safe Mode, you will get a message as shown below
Here is a simple, portable tool called SafeMSI.exe designed to let you easily uninstall programs in safe mode.
This utility will do a registry tweak and launch the Windows Installer service with a click; you don’t need to edit the registry by hand. If you want to uninstall a program in safe mode, just run the tool SafeMSI.exe in Safe Mode.
The tool is compatible with Windows 2000, XP, Vista and 7 (I tested it with windows 7) and can be download it free at source.